Psoriatic Disease

Psoriatic Disease
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The Immune System

The immune system is your body’s defence against disease and pathogens.[1] In immune-mediated inflammatory diseases, the immune system wrongly attacks its own tissues and causes inflammation, pain, and can result in loss of function.[2][3]

At Janssen, we are focusing our scientific expertise on creating ways to restore the body’s immune balance. We’re committed to discovering new medicines that will redefine the way we maintain immune-mediated health.

Janssen & Psoriatic Disease

Janssen’s worldwide leadership in immunology has been established from a 30-year heritage of innovation and scientific breakthroughs. For over two decades, we have been a world leader in the development of biologic treatments that have modified the imbalance in patients’ immune systems and have transformed their lives.

We foster active collaborations with academia, emerging companies, patients, and patient groups to accelerate innovation and achieve our shared goals in tackling immune-mediated disease.

Beyond Expectations

Beyond Expectations

Explore our Disease Areas

Psoriasis (Pso)

Psoriasis is an immune system-related skin disorder.[4] It can manifest in a few different ways and can appear anywhere on your body, often in itchy, sometimes painful, red patches or silvery scales.[5] It can also cause thick, pitted or ridged nails.[5] Approximately 30% of people who have Pso later develop PsA (see below).[6]

Psoriatic Arthritis (PsA)

Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory disease that affects the joints.[6] It is a form of arthritis that affects some people who have psoriasis,[7] though some people never develop psoriasis, or develop PsA first.[6] The most common symptoms of PsA are pain, stiffness and swelling in your joints.[7]

References

Mayo Clinic. Psoriasis Symptoms and Causes. Available at: https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840. Accessed: December 2023.
National Psoriasis Foundation. Life with Psoriasis. Available at: https://www.psoriasis.org/life-with-psoriasis/ Accessed: December 2023
NHS. Living with Psoriasis. Available at: https://www.nhs.uk/conditions/psoriasis/living-with/ Accessed: December 2023
National Psoriasis Foundation. About Psoriasis. Available at: https://www.psoriasis.org/about-psoriasis/ Accessed: December 2023
The Psoriasis and Psoriatic Arthritis Alliance (PAPAA). Psoriasis: a simple explanation. Available at: https://www.papaa.org/learn-about-psoriasis-and-psoriatic-arthritis/common-questions/psoriasis-a-simple-explanation/ Accessed: December 2023
Arlington Dermatology. A look at the types of Psoriasis. Available at: A Look at the Types of Psoriasis - Arlington Dermatology. Accessed: December 2023
National Psoriasis Foundation. Inverse Psoriasis. Available at: https://www.psoriasis.org/inverse-psoriasis/ Accessed: December 2023
National Psoriasis Foundation: Pustular Psoriasis. Available at: https://www.psoriasis.org/pustular/ Accessed: December 2023
National Psoriasis Foundation: Erythrodermic Psoriasis. Available at: https://www.psoriasis.org/erythrodermic-psoriasis/ Accessed: December 2023
National Psoriasis Foundation. Psoriasis Statistics. Available at: Get the Facts About Psoriasis and Psoriatic Arthritis : National Psoriasis Foundation Accessed: December 2023.
European Parliament. Parliamentary Question: EU action on psoriasis. Available at: Parliamentary question | EU action on psoriasis | E-010237/2012 | European Parliament (europa.eu) Accessed: January 2024.
Rachakonda, T.D. , Schupp, C. W. , Armstrong, A. W., Psoriasis prevalence among adults in the United States. 2014 March, 70(3):512-6
VeryWellHealth.com How Psoriasis is diagnosed. Available at: https://www.verywellhealth.com/how-psoriasis-is-diagnosed-2788316 Accessed: December 2023
Mayo Clinic. Psoriasis Diagnosis and Treatment. Available at: https://www.mayoclinic.org/diseases-conditions/psoriasis/diagnosis-treatment/drc-20355845 Accessed: December 2023
World Health Organization. Global Report on Psoriasis. 2016. Available at: 9789241565189_eng.pdf;jsessionid=59BF358B7BAF831581BEE9D2E728D5D0 (who.int) Accessed: January 2024
Rapp SR, et al. J Am Acad Dermatol 1999;41:401–7
Pompili, M., et al (2016). Suicide risk and psychiatric comorbidity in patients with psoriasis. The Journal of international medical research, 44(1 suppl), 61–66.
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